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Likelier
Peer-reviewed Journal of Laryngology & Otology (Mirza S, Richardson H)

Otic barotrauma from air travel

Cited in 2 Likelier entries (1 risk, 1 decision).

Used in 2 entries

For each citing entry, the verbatim excerpt and Likelier's calculation notes (how the source's number was converted to the lifetime-probability framing) are shown below. Click through to read the full claim ledger.

  1. Statistic
    Otic barotrauma is a common problem in air travellers; middle-ear pressure changes during descent are the dominant mechanism; topical and oral decongestants are the main evidence-based prophylaxis with modest effect sizes in randomised trials
    “"Otic barotrauma occurring during air travel involves traumatic inflammation of the middle ear, caused by a pressure difference between the air in the middle ear and the external atmosphere, developing after ascent or more usually descent."”
    Calculation notes
    Mirza & Richardson is the canonical narrative review of air-travel otic barotrauma, published in J Laryngol Otol 119(5):366-70. The paper does not supply a single headline incidence figure — it summarises the fragmentary passenger and aircrew epidemiology and the three randomised decongestant trials available at the time — so we use it as the mechanistic and methodological anchor, not the quantitative anchor. The paper's core clinical claim, that a blocked Eustachian tube cannot equilibrate cabin-pressure changes during descent and that this is the direct mechanism of barotrauma, is the foundation for the "URI flight = higher rate" step in the native calculation. The 10-20 percent baseline adult rate and the 26-55 percent child rate cited in the Native field trace back through this review to Stangerup, Klokker, Csortan/Jones, and the Tonkin/Fagan series.
    

    Independence note: Mirza & Richardson synthesise the Stangerup auto-inflation trials and the Csortan/Jones pseudoephedrine RCT; treat it as an editorially independent review of primary data that overlaps methodologically with both the Wright BMJ review and the Rosenkvist pilot survey cited below.

    Source date: 2005-05-01 · Accessed: 2026-04-16

  2. [2] Postpone sick trip vs. travel Decision · inaction side
    Statistic
    Narrative review of air-travel otic barotrauma: traumatic inflammation of the middle ear caused by a pressure difference between the middle ear and external atmosphere, developing most often on descent because of failure of the eustachian tube to equilibrate pressures. It is a common problem presenting with ear fullness, otalgia, and deafness; severe cases may result in tympanic-membrane perforation and even round-window-membrane rupture. Of three randomized controlled trials reviewed, one found oral pseudoephedrine reduced otalgia in adults with recurrent ear pain during air travel, another found oral pseudoephedrine did not decrease in-flight ear pain in children, and a third found oxymetazoline nasal spray produced no statistically significant symptom reduction in adults
    “"Otic barotrauma occurring during air travel involves traumatic inflammation of the middle ear, caused by a pressure difference between the air in the middle ear and the external atmosphere, developing after ascent or more usually descent. The pressure difference occurs because of failure of the eustachian tube to equilibrate middle ear and atmospheric pressures. It is a common problem, presenting with ear fullness, otalgia and deafness. Severe cases may result in tympanic membrane perforation and even round window membrane rupture. Of three randomized controlled trials, one showed that oral pseudoephedrine decongestants reduced otalgia in adults with recurrent ear pain during air travel, whilst another found that oral pseudoephedrine did not decrease in-flight ear pain in children."”
    Calculation notes
    Mirza & Richardson 2005, J Laryngol Otol 119(5):366-70. This narrative review establishes that otic barotrauma is a common, descent-dominated problem in air travellers and that decongestant prophylaxis has only modest, mixed effect sizes across three randomized trials — it does not itself report a per-flight prevalence rate. Barotrauma is the modal adverse outcome underlying inaction-side regret: not catastrophic, not requiring hospitalization, but vivid enough to produce strong retrospective regret. A traveler whose ear stays popped for the entire return week, or whose toddler screams through descent, is precisely the high- salience post-decision regret event this entry is built around. The quantitative per-URI-flight barotrauma probability math lives in the Likelier [[flying-with-uri]] fear entry; this entry uses Mirza & Richardson to characterise the mechanism and modal severity, and re-frames the outcome as the substrate for inaction-side regret.
    

    Source date: 2005-05-01 · Accessed: 2026-05-24

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